Black pepper contains antioxidants and may support your overall health. Benefits can include reducing inflammation and supporting blood sugar control and brain health, among others.Black pepper is one of the most commonly used spices worldwide.It’s made by grinding peppercorns, which are dried berries from the vine Piper nigrum.It has a sharp and mildly spicy flavor that goes well with many dishes.But black pepper is more than just a kitchen staple. It has been deemed the “king of spices” and used in ancient Ayurvedic medicine for thousands of years due to its high concentration of potent, beneficial plant compounds.